some in-depth discussion of early lsd research from The Sun outta Chapel Hill…
from http://www.thesunmagazine.org/issues/404/across_the_universe
The research protocol was a combination of lsd and exposure to a powerful stroboscopic light of various frequencies to study the effects of lsd on what is called “driving” or “entraining” the brain waves. When my experience was culminating, the research assistant took me to a small room for my eeg and put the electrodes on my scalp. I lay down and closed my eyes, and then she turned on a strobe. There was an incredible light, more powerful than anything I had ever seen in my life. At the time I thought it must have been what it was like to see the atomic bomb fall on Hiroshima. Today I think it was more like the “primary clear light,” or dharmakaya, which the Tibetan Book of the Dead says we are supposed to see at the time of our death.
Winter: What were the results of that initial lsd study?
Grof: We found that when we gave lsd or another psychedelic substance in the same dosage under the same circumstances to a number of people, each of them had a completely different experience. Even if the same person took the same substance multiple times, each of the sessions would be different. So we were not dealing with a predictable pharmacological effect. If you have no idea what might happen when you give someone a substance, that is the end of its use as a traditional pharmacological agent.
But in the course of this research it became clear that lsd was opening access to deep levels of the unconscious. So I dropped the experimental-psychosis approach and took lsd into clinical studies.
As the music’s tempo increased and the beats became tribal, some of the breathers entered what seemed to be a trance state. A woman beside us began to make intricate arm movements, her eyes rolled back in her head. Bruno was sweating profusely, his hands curled into hard, tight fists. I heard groans, screams, and what sounded like the wail of an infant coming from a nearby woman in her sixties. Grof sat alone at the head of the room as the facilitators supported the pairs of partners. Every now and then he’d tour the room, like a psychiatrist emeritus making rounds. I became accustomed to seeing his champagne-colored dress socks in my peripheral vision whenever he walked by.
Near the end of the breathing session, Bruno reported feeling tension in the area around his sacrum, where the spinal column meets the pelvis. Grof offered to help release it, and Bruno accepted. When Bruno began to experience nausea, Grof motioned for me to make ready the plastic bag given to sitters. (We’d been told that vomiting is one of the possible outcomes of a breathwork session.) And my partner did throw up as Grof pressed on his sacrum, back, and diaphragm. Though I was distressed, Grof showed no revulsion or hesitation. When the session was over, I helped my partner rise; his muscles had cramped so intensely that he could barely walk. We went outside and sat in the sun, and he told me he was glad he’d had the experience, despite the muscle pain and vomiting, because he’d been able to release difficult emotions that he’d held in for some time.
Next it was my turn as breather. I was nervous lying on the sleeping bag as Grof led us through the relaxation exercise and breathing instruction. My breathing felt artificial and forced at first, but I tried to relax and focus instead on sensations in my body, the first of which was a prickly, buzzing feeling in my hands. My fingers soon clenched into tight, painful fists. Worried this would continue for hours, I breathed through the pain until I felt an unusual rippling sensation under my arms. Then I felt as if my body were being tugged upward off the floor and through the air, and suddenly my consciousness inhabited the body of a red-tailed hawk soaring over the ocean. With each beat of my wings I felt my sinew and bone moving delicately and powerfully. I saw minute details at a vast distance. At the same time I could still feel my body on the floor of the hotel ballroom, where my breathing had shifted into an easy rhythm and my hands had relaxed. I reveled in the freedom of flight at the beginning of my journey into the nonordinary.